OUR FOCUSUlcerative colitis, a form of inflammatory bowel disease (IBD) characterized by chronic inflammation of the colon.
PREVALENCEAffects 9–20 per 100,000 globally, with higher rates in North America and Europe; rising incidence in newly industrialized countries.
IMPACTLeads to symptoms such as abdominal pain, diarrhea, rectal bleeding, and can significantly reduce patient quality of life.
In the pipeline (Phase 2):
INDICATIONTargeted treatments (in development) for inflammation limited to the distal colon/rectum.
PREVALENCERepresents a subset of UC, requiring local/topical therapy approaches for optimal outcomes.
IMPACTProctitis and left-sided disease are significant causes of symptoms and healthcare utilization in UC patients.